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American Journal of Public Health Research. 2022, 10(2), 42-52
DOI: 10.12691/AJPHR-10-2-2
Review Article

Ethical Considerations in Clinical Research: A Comprehensive Review

Venkataramana Kandi1, and Sabitha Vadakedath1

1Prathima Institute of Medical Sciences, Telangana, India

Pub. Date: March 01, 2022
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Cite this paper

Venkataramana Kandi and Sabitha Vadakedath. Ethical Considerations in Clinical Research: A Comprehensive Review. American Journal of Public Health Research. 2022; 10(2):42-52. doi: 10.12691/AJPHR-10-2-2

Abstract

Clinical studies involve research that is carried out in human beings and has direct implications on the health of people who participate in it as study subjects. Moreover, clinical trials are performed on healthy and diseased human subjects, wherein the safety and efficacy of a novel drug/device are tested. Therefore, the study design and the subject recruitment assumes increased significance. In this review we attempt to comprehensively discuss the importance of ethics in clinical research and specific ethical considerations concerning the evaluation of medical products, epidemiological studies, human genetics, and genomic research, transplantation studies, reproductive procedures/interventions, research among geriatric and pediatric populations and research involving the development of vaccines and diagnostic devices.

Keywords

clinical studies, clinical research, human subjects, ethics, ethical considerations, vaccines, devices, medical products

Copyright

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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