Treatment Adherence among Tuberculosis and Human Immuno Deficiency Virus Coinfected Patients in Ginnir Referral Hospital

Ahmed Yasin Mohammed^1, and Muhammedawel Kaso Adem¹

¹Department of Public Health, College of Medicine and Health Science, Madawalabu University, Bale Goba

Cite this paper

Ahmed Yasin Mohammed and Muhammedawel Kaso Adem. Treatment Adherence among Tuberculosis and Human Immuno Deficiency Virus Coinfected Patients in Ginnir Referral Hospital. American Journal of Public Health Research. 2014; 2(6):239-243. doi: 10.12691/AJPHR-2-6-4

Abstract

Tuberculosis is a major public health problem in Ethiopia, and a high number of TB patients are co-infected with HIV. There is a need for more knowledge about factors influencing treatment adherence in co-infected patients on concomitant treatment. The objective of this study is to assess treatment adherence among TB/HIV co infected patients in Ginnir referral hospital from March - April 2013. Institution based cross sectional study design was used to collect, analyze and summarize data from TB/HIV co-infected patients. The data was sorted manually and scientific calculator was used to compile and express in table and graphs. Descriptive statistics like frequencies, mean and median were used to analyze the data. Prior to data collection, permission request was obtained from Madawalabu University, Goba campus and it was submitted to Ginnir referral hospital’s medical director. Respondents were told about the objective of this study, reassured for confidentiality and asked for consent. The results shown among the 53 TB/HIV co- infected patients, 11(20.7%) had missed taking both ARV and anti TB drugs at least once. Of these, 4 (36.4%) had missed the ARV treatment while remaining 7(63.6%) of them missed the anti TB medication. The result showed that, the main reason for missing the drugs was forgetting taking medication 6(54.6%). It can be concluded that the level of non adherence is relatively high and the main reason behind was forgetting distance from health institution and income related problems. Intervention s to reduce it need to be instituted such as adherence educations should have to be given for the patients to take the treatment by the recommended schedule and also family members and supporters should have to be told to remind and follow them carefully. On the other hand bringing the health service nearby might alleviate the problem of distance. In order to deal with the income related problems, Ginnir referral hospital should have to work in collaboration with NGOs and other fund raising institutions.

Keywords

Treatment adherence, tuberculosis and human immuno deficiency virus co-infected patients

Copyright

This work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References

[1]	Swaminath S, Padmapaiyadarsini C and Narendran G (2011). HIV-Associated Tuberculosis. J Manag Care Pharm, 17(3), 213-23.
[2]	World Health Organization (2007). Global Tuberculosis Control: Surveillance, Planning, Financing. WHO report.
[3]	Afework K, Mengistu G, Ayele B (2007).Co-infection and clinical manifestation of TB in HIV infected and uninfected adults at teaching hospital. J Microbial Immunol Infect. 25, 135-143.
[4]	Demissie M, Lindtjon B, Tegbaru B (2000).Human Immunodeficiency virus (HIV) infection in tuberculosis patients. J Health Dev, 60, 564-674.
[5]	Anthony Harries Stephen Graham Dermot Maher (2004). Department of child and adolescent health and development, World Health Organization,2nd edition.
[6]	Shargie EB, Lindtjørn B (2007). Determinants of treatment adherence among smear-positive pulmonary tuberculosis patients. Journal pmed, 4(2), e37.
[7]	Chesney MA, Morin M, Sherr L (2000). Adherence to HIV combination therapy. Soc Sci Med, 50, 1599-1605.
[8]	Farmer P (1997). Social scientists and the new tuberculosis. Soc Sci Med. 44, 347-358.
[9]	Wares DF, Singh S et al (2003). Non-adherence to tuberculosis treatment, Soc Sci Med, 7, 327-335.
[10]	Amare D, Markos T, Yohannis H (2009). TB and HIV co infection its impact on quality of life. Soc Sci Med, 8, 212-230.
[11]	Munro SA, Lewin SA, Smith H, Engel ME, Fretheim A, et al (2007). Patient adherence to tuberculosis treatment: A systematic review of qualitative research. PLoS Med, 4(7), e238.
[12]	Mekdes K, Gunnar A, Jane F (2010). Barriers and facilitators of adherence to TB treatment in patients on concomitant TB and HIV treatment PLoS Med, 1471-2458.
[13]	Mkopi A, Range N, Lwilla F, Egwaga S, Schulze A, et al (2012). Adherence to Tuberculosis Therapy among Patients Receiving Home-Based Directly Observed Treatment: Evidence from the United Republic of Tanzania. PLoS ONE, 7(12), e51828.
[14]	Nackers F, Huerga H, Espie´ E, Aloo AO, Bastard M, et al (2012). Adherence to Self-Administered Tuberculosis Treatment in a High HIV-Prevalence Setting: A Cross-Sectional Survey in Homa Bay, Kenya. PLoS ONE, 7(3), e32140.
[15]	Estifanos Biru, Bernt Lindtjorn (2007). Determinants of treatment adherence among smear-positive pulmonary TB patients in South Ethiopia, 122-130.
[16]	Wondimeneh Y, Muluye D, Belyhun Y (2012). Prevalence of PTB and immunological profile of HIV-co infected patient in North west Ethiopia, 456-460.
[17]	Monica G, Paul K, Freddy E (2009). Non-adherence to anti-TB drugs among TB/HIV co-infected patients in Mbarara Hospital Uganda. African Health Sciences, 9 (1), 326-371.
[18]	Adams SA, Soumeraj BS, Jonathan L, Doss-Degan D (1999). Evidence of self report bias in assessing adherence to guidelines. International Journal for Quality in Health Care, 187-192.
[19]	Kebede A and Wube K (2012). Medication adherence and its determinants among patients on concomitant tuberculosis and anti retroviral therapy. North American journal of medical science, 4(2), 60-69.
[20]	Jaiswal A, Singh V, Ogden J.A et al (2003). Adherence to tuberculosis treatment: lessons from the urban setting of Delhi, India. Tropical medicine and international health, 8(7), 625-633.